A dynamic model of the body gas stores for carbon dioxide, oxygen, and inert gases that incorporates circulatory transport delays to and from the lung-Reference-Cited by-同舟云学术

A dynamic model of the body gas stores for carbon dioxide, oxygen, and inert gases that incorporates circulatory transport delays to and from the lung

Published:2021-05-01 Issue:5 Volume:130 Page:1383-1397
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Magor-Elliott Snapper R. M.¹,Fullerton Christopher J.¹,Richmond Graham²,Ritchie Grant A. D.²,Robbins Peter A.¹^ORCID

Affiliation:

1. Department of Physiology, Anatomy and Genetics, University of Oxford, United Kingdom;

2. Department of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, United Kingdom

Abstract

A model for the body gas stores has been generated that is applicable to both respiratory gases (CO2 and O2) and inert gases. It is based on anatomical details for organ volumes and blood contents together with anatomical details of the large arteries. It can be scaled to the body size and composition of different individuals. The model enables mixed venous gas compositions to be predicted from the systemic arterial compositions.

Funder

British Heart Foundation

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00764.2020

Reference56 articles.

1. DYNAMICS OF CHANGES IN CARBON DIOXIDE STORES

2. Physiological Parameter Values for Physiologically Based Pharmacokinetic Models

3. STRUCTURE AND QUANTIFICATION OF A PHYSIOLOGICAL MODEL OF THE DISTRIBUTION OF INJECTED AGENTS AND INHALED ANAESTHETICS

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Missing: population‐level studies of tissue oxygenation in health and disease;The Journal of Physiology;2023-12-08

2. Computed cardiopulmonography and the idealized lung clearance index, iLCI_2.5, in early-stage cystic fibrosis;Journal of Applied Physiology;2023-07-01

3. Criticality of isolation valves in water distribution networks with hydraulics and topology;2023-01-10

4. Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography;Journal of Applied Physiology;2022-11-01