Relative hypoxemia at depth during breath-hold diving investigated through arterial blood gas analysis and lung ultrasound

Author:

Paganini Matteo1ORCID,Moon Richard E.2ORCID,Giacon Tommaso Antonio1ORCID,Cialoni Danilo3ORCID,Martani Luca4,Zucchi Lorenzo5,Garetto Giacomo6,Talamonti Ennio1,Camporesi Enrico M.7,Bosco Gerardo1

Affiliation:

1. Department of Biomedical Sciences, University of Padova, Padova, Italy

2. Department of Anesthesiology, Center for Hyperbaric Medicine and Environmental Physiology, Duke University Medical Center, Durham, North Carolina, United States

3. Europe Research Division, Divers Alert Network (DAN), Roseto degli Abruzzi, Italy

4. Hyperbaric Medicine Unit, Vaio Hospital, Fidenza, Italy

5. Emergency Medicine Residency Program, Department of Medicine (DIMED), University of Padova, Padova, Italy

6. ATIP Center for Hyperbaric Medicine, Padova, Italy

7. TEAMHealth Research Institute, Tampa General Hospital, Tampa, Florida, United States

Abstract

During breath-hold diving, arterial partial pressure of oxygen ([Formula: see text]) and arterial partial pressure of carbon dioxide ([Formula: see text]) are believed to increase progressively during descent, as explained by theory, previous end-tidal alveolar gas measurements, and arterial blood gas analysis in hyperbaric chambers. Recent experiments in real underwater environment found a paradoxical [Formula: see text] drop at depth in some divers. This work confirms that some breath-hold divers can experience hypoxemia at depth. The hypothesized explanation for such a discrepancy is lung atelectasis, as suggested by lung ultrasound findings.

Funder

DOD | USN | Office of Naval Research

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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