Pulmonary blood volume measured by 82Rb-PET in patients with chronic obstructive pulmonary disease: a retrospective cohort study

Author:

Hartmann Jacob Peter123ORCID,Lassen Martin Lyngby23ORCID,Mohammad Milan12ORCID,Iepsen Ulrik Winning14ORCID,Mortensen Jann2ORCID,Hasbak Philip2,Berg Ronan M. G.1235ORCID

Affiliation:

1. Centre for Physical Activity Research, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark

2. Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital—Rigshospitalet, Copenhagen, Denmark

3. Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

4. Department of Anaesthesiology and Intensive Care, Copenhagen University Hospital—Hvidovre, Copenhagen, Denmark

5. Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, United Kingdom

Abstract

The present study demonstrated that patients with chronic obstructive pulmonary disease (COPD) exhibit central hypovolemia compared with healthy controls. Pulmonary blood volume may thus be a relevant physiological and/or clinical outcome measure in future COPD studies.

Funder

Helsefonden

Rigshospitalet

TrygFonden

Publisher

American Physiological Society

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