Decrease in work rate in order to keep a constant heart rate: biomarker of exercise intolerance following a 10-day bed rest-Reference-Cited by-同舟云学术

Decrease in work rate in order to keep a constant heart rate: biomarker of exercise intolerance following a 10-day bed rest

Published:2022-06-01 Issue:6 Volume:132 Page:1569-1579
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Baldassarre Giovanni¹^ORCID,Zuccarelli Lucrezia¹,Manferdelli Giorgio²,Manfredini Valentina¹,Marzorati Mauro²^ORCID,Pilotto Andrea¹²,Porcelli Simone²³^ORCID,Rasica Letizia²,Šimunič Boštjan⁴^ORCID,Pišot Rado⁴,Narici Marco⁵,Grassi Bruno¹^ORCID

Affiliation:

1. Department of Medicine, University of Udine, Udine, Italy

2. Institute of Biomedical Technologies, National Research Council, Segrate, Italy

3. Department of Molecular Medicine, University of Pavia, Pavia, Italy

4. Institute for Kinesiology Research, Science and Research Center, Koper, Slovenia

5. Department of Biomedical Sciences, University of Padova, Padua, Italy

Abstract

During a 15-min exercise carried out at a heart rate (HR) slightly above that corresponding to the gas exchange threshold, to keep HR constant, work rate significantly decreased; the decrease was more pronounced after a 10-day horizontal bed rest. The work rate decrease at a fixed HR can be considered a systemic biomarker of exercise intolerance during microgravity/inactivity and could also be easily and reliably determined during spaceflights or in patients.

Funder

Agenzia Spaziale Italiana

Ministero dell'Istruzione, dell'Università e della Ricerca

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00052.2022

Reference55 articles.

1. Riebe D, Ehrman JK, Liguori G, Magal M. ACSM’s Guidelines for Exercise Testing and Prescription (10th ed). Philadelphia, PA: Wolters Kluwer Health, 2018, p. 231–249.

2. Powers SK, Howley ET. Exercise Physiology: Theory and Application to Fitness and Performance. New York: McGraw-Hill, 2004, p. 333–336.

3. Astrand PO, Rodahl K, Dahl HA, Stromme SB. Textbook of Work Physiology: Physiological Bases of Exercise (4th ed.). New York: McGraw-Hill, 2003, p. 363–384.

4. Comparison between Slow Components of HR and V˙O2 Kinetics: Functional Significance

5. Slow Component of V˙O2 Kinetics

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