The impact of exercise training on muscle sympathetic nerve activity: a systematic review and meta-analysis

Author:

Meyer Sarah E.1,Kimber Miranda1,Maier Lauren E.1,Matenchuk Brittany1,Moldenhauer Ramiah1,de Waal Stephanie1,Sivak Allison2,Davenport Margie H.1ORCID,Steinback Craig 'D.1ORCID

Affiliation:

1. Neurovascular Health Laboratory, Program for Pregnancy and Postpartum Health, Women and Children’s Health Research Institute, Alberta Diabetes Institute, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada

2. H. T. Coutts Education & Physical Education Library, University of Alberta, Edmonton, Alberta, Canada

Abstract

This systematic review and meta-analysis suggests exercise training reduces muscle sympathetic nerve activity (MSNA), which may be valuable for improving cardiovascular health. The reduction in burst incidence was greater among individuals with cardiovascular disease when compared with those without; exercise training may be particularly beneficial for individuals with cardiovascular disease. Meta-regression analyses demonstrated a dose-response relationship, where individuals with higher sympathetic activity preintervention had greater reductions in sympathetic activity post-intervention.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

University of Alberta

Publisher

American Physiological Society

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