Selectivity and excitability of upper-limb muscle activation during cervical transcutaneous spinal cord stimulation in humans-Reference-Cited by-同舟云学术

Selectivity and excitability of upper-limb muscle activation during cervical transcutaneous spinal cord stimulation in humans

Published:2021-08-01 Issue:2 Volume:131 Page:746-759
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

de Freitas Roberto M.¹,Sasaki Atsushi²³^ORCID,Sayenko Dimitry G.⁴,Masugi Yohei²⁵,Nomura Taishin¹^ORCID,Nakazawa Kimitaka²,Milosevic Matija¹^ORCID

Affiliation:

1. Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Japan

2. Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Meguro, Japan

3. Japan Society for the Promotion of Science, Chiyoda, Japan

4. Department of Neurosurgery, Center for Neuroregeneration, Houston Methodist Research Institute, Houston, Texas

5. Institute of Sports Medicine and Science, Tokyo International University, Kawagoe, Japan

Abstract

We examined selectivity and excitability of motor activation in multiple upper-limb muscles during cervical transcutaneous spinal cord stimulation with different cathode and anode configurations. Hand muscles were more activated when the cathode was configured over the T1 vertebra compared with C6 and C7 locations. Higher stimulation intensities were required to activate distal hand muscles than proximal arm muscles. Finally, configuration of anode over anterior neck elicited larger responses compared with other configurations.

Funder

MEXT | Japan Society for the Promotion of Science

Global Center for Medical Engineering and Informatics at Osaka University

MEXT | Engineering Science for the 21st Century

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00132.2021

Reference58 articles.

1. Engaging Cervical Spinal Cord Networks to Reenable Volitional Control of Hand Function in Tetraplegic Patients