Intermittent short-arm centrifugation is a partially effective countermeasure against upright balance deterioration following 60-day head-down tilt bed rest-Reference-Cited by-同舟云学术

Intermittent short-arm centrifugation is a partially effective countermeasure against upright balance deterioration following 60-day head-down tilt bed rest

Published:2021-08-01 Issue:2 Volume:131 Page:689-701
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

De Martino Enrico¹^ORCID,Salomoni Sauro E.²^ORCID,Hodges Paul W.²^ORCID,Hides Julie³,Lindsay Kirsty¹,Debuse Dorothée¹,Winnard Andrew¹,Elliott James⁴⁵,Hoggarth Mark⁴⁶,Beard David⁷,Cook Jonathan A.⁷⁸,Ekman Robert⁹,Hinterwaldner Luis⁹,Scott Jonathan⁹¹⁰,Weber Tobias⁹¹⁰,Caplan Nick¹

Affiliation:

1. Aerospace Medicine and Rehabilitation Laboratory, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom

2. National Health and Medical Research Council Centre for Clinical Research Excellence in Spinal Pain, Injury and Health, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia

3. School of Health Sciences and Social Work, Griffith University, Nathan Campus, Brisbane, Australia

4. Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois

5. Northern Sydney Local Health District and The University of Sydney, Faculty of Medicine and Health, The Kolling Research Institute Sydney, Australia

6. Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois

7. National Institute for Health Research Oxford Biomedical Research Centre, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

8. Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

9. European Astronaut Centre, Space Medicine Team (HRE-OM), European Space Agency, Cologne, Germany

10. KBR GmbH, Cologne, Germany

Abstract

This study presents novel insights into the effect of artificial gravity (AG) on the deterioration of standing balance and anticipatory postural adjustments (APAs) of trunk muscles induced by 60-day strict head-down bed rest. The results indicated severe balance dysfunction and delayed APAs during rapid arm movement. AG partially mitigated the deterioration in standing balance and may thus be considered as a potential countermeasure for future planetary surface explorations. Optimization of AG protocols might enhance effects.

Funder

Department of Health, Australian Government | National Health and Medical Research Council

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00180.2021

Reference71 articles.

1. Human Pathophysiological Adaptations to the Space Environment

2. Analogs of microgravity: head-down tilt and water immersion

3. Adaptation of postural control to weightlessness