Asymmetry of flow in aortic root and its application in hypertrophic obstructive cardiomyopathy

Author:

Francis Nadine12ORCID,Hosny Mohammed34ORCID,Yacoub Magdi H.1567ORCID,Parker Kim H.2ORCID

Affiliation:

1. Biomedical Engineering and Innovation Laboratory, Aswan Heart Centre, Department of Research, Magdi Yacoub Heart Foundation, Aswan, Egypt

2. Department of Bioengineering, Imperial College, London, United Kingdom

3. Department of Cardiology, Aswan Heart Centre, Magdi Yacoub Heart Foundation, Aswan, Egypt

4. Department of Cardiology, Cairo University, Cairo, Egypt

5. Department of Cardiac Surgery, Aswan Heart Centre, Magdi Yacoub Heart Foundation, Aswan, Egypt

6. The Magdi Yacoub Institute, Harefield Hospital, Harefield, United Kingdom

7. National Heart and Lung Institute, Imperial College, London, United Kingdom

Abstract

The aortic root is a vital organ responsible for performing sophisticated functions to regulate the blood flow dynamics during the cardiac cycle. Such synchronized complex performance affects and is affected by the flow symmetry and type of flow reaching the aorta. Here, we report flow asymmetry in the aortic root which could have clinical implications, and we investigate the potential of various quantitative parameters as measures of flow asymmetry in hypertrophic obstructive cardiomyopathy.

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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