Dynamic airway function during exercise in COPD assessed via impulse oscillometry before and after inhaled bronchodilators-Reference-Cited by-同舟云学术

Dynamic airway function during exercise in COPD assessed via impulse oscillometry before and after inhaled bronchodilators

Published:2021-07-01 Issue:1 Volume:131 Page:326-338
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Tiller Nicholas B.¹,Cao Min¹²,Lin Fang¹³,Yuan Wei¹³,Wang Chu-Yi⁴,Abbasi Asghar¹,Calmelat Robert¹,Soriano April¹,Rossiter Harry B.¹,Casaburi Richard¹,Stringer William W.¹^ORCID,Porszasz Janos¹

Affiliation:

1. Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

2. Department of Respiratory and Critical Care Medicine, Beijing Chest Hospital, Capital Medical University, Beijing, People’s Republic of China

3. Department of Respiratory, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China

4. Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, California

Abstract

This study provides a novel, mechanistic insight into dynamic airway function during exercise in COPD, before and after inhaled bronchodilators. The use of impulse oscillometry (IOS) to evaluate airway function is unique among exercise studies. We show strong correlations among IOS variables, dynamic hyperinflation, and shape-changes in the spontaneous expiratory flow-volume curve. This approach may aid in clinical assessment of airway function during exercise.

Funder

NIH

Tobacco-Related Disease Research Program

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00148.2021

Reference54 articles.

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