Effects of head-down tilt bed rest plus elevated CO2 on cognitive performance

Author:

Basner Mathias1ORCID,Stahn Alexander C.1,Nasrini Jad1,Dinges David F.1,Moore Tyler M.2,Gur Ruben C.2,Mühl Christian3,Macias Brandon R.4,Laurie Steven S.5

Affiliation:

1. Division of Sleep and Chronobiology, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania

2. Brain Behavior Laboratory, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania

3. Department of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center, Cologne, Germany

4. NASA Johnson Space Center, Houston, Texas

5. KBR, Houston, Texas

Abstract

NEW AND NOTEWORTHY This study investigated the effects of prolonged head-down tilt bed rest with and without elevated (3.73 mmHg) levels of ambient CO2 on cognitive performance across a range of cognitive domains and is one of the few studies investigating combined effects of environmental stressors prevalent in spaceflight. The study showed moderate declines in cognitive speed induced by head-down tilt bed rest and suggests that exposure to elevated levels of ambient CO2 did not modify this effect.

Funder

National Aeronautics and Space Administration

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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