Leucine augments specific skeletal muscle mitochondrial respiratory pathways during recovery following 7 days of physical inactivity in older adults-Reference-Cited by-同舟云学术

Leucine augments specific skeletal muscle mitochondrial respiratory pathways during recovery following 7 days of physical inactivity in older adults

Published:2021-05-01 Issue:5 Volume:130 Page:1522-1533
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Arentson-Lantz Emily J.¹²,Mikovic Jasmine³,Bhattarai Nisha⁴,Fry Christopher S.¹²,Lamon Séverine³,Porter Craig⁴,Paddon-Jones Douglas¹²

Affiliation:

1. Department of Nutrition and Metabolism, University of Texas Medical Branch, Galveston, Texas

2. Center for Recovery, Physical Activity and Nutrition, University of Texas Medical Branch, Galveston, Texas

3. Faculty of Health, Institute for Physical Activity and Nutrition (IPAN), Deakin University, Melbourne, Victoria, Australia

4. Deparment of Surgery, University of Texas Medical Branch, Galveston, Texas

Abstract

In older adults, leucine mitigated the loss of insulin sensitivity associated with muscular disuse. Leucine supplementation increased mitochondrial respiration and reduced a marker of oxidative stress following periods of disuse and rehabilitation.

Funder

HHS | NIH | National Institute of Nursing Research

HHS | NIH | National Center for Research Resources

HHS | NIH | National Center for Advancing Translational Sciences

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00810.2020

Reference49 articles.

1. The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health, Aging and Body Composition Study

2. Chronological Age Does not InfluenceEx-vivoMitochondrial Respiration and Quality Control in Skeletal Muscle

3. Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle

4. Sarcopenia: Prevalence, Mechanisms, and Functional Consequences

5. Mitochondrial oxidative stress in aging and healthspan

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A multimodal exercise countermeasure prevents the negative impact of head‐down tilt bed rest on muscle volume and mitochondrial health in older adults;The Journal of Physiology;2024-06-15

2. Leucine Supplementation Prevents the Development of Skeletal Muscle Dysfunction in a Rat Model of HFpEF;Cells;2024-03-13

3. Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage;Free Radical Biology and Medicine;2024-02

4. Lifestyle effects on aging and CVD: A spotlight on the nutrient-sensing network;Ageing Research Reviews;2023-12

5. Loss of Muscle Mass and Strength After Hip Fracture: an Intervention Target for Nutrition Supplementation;Current Osteoporosis Reports;2023-11-29