Acute aerobic exercise regulation of myocardial calcium homeostasis involves CASQ1, CASQ2, and TRDN-Reference-Cited by-同舟云学术

Acute aerobic exercise regulation of myocardial calcium homeostasis involves CASQ1, CASQ2, and TRDN

Published:2023-10-01 Issue:4 Volume:135 Page:707-716
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Ma Jiacheng¹^ORCID,Pang Xiaoli¹,Wang Tutu¹,Ning Miaomiao¹,Liang Yu¹,Li Xiaole¹,Tian Xinyu¹,Mo Yurou¹,Laher Ismail²^ORCID,Li Shunchang¹^ORCID

Affiliation:

1. Institute of Sports Medicine and Health, Chengdu Sport University, Chengdu, People’s Republic of China

2. Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

Abstract

Acute aerobic exercise upregulates myocardial Casq1, Casq2, and Trdn genes and the proteins they encode in rats. Higher protein levels of CASQ1, CASQ2, and TRDN conferred an improved ability of the myocardium to resist calcium overload. Furthermore, 24 h postexercise is the time point with optimal myocardial calcium buffer capacity.

Funder

National Nature Sicence Foundation of China

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00299.2023

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