An integrated mathematical model of the cardiovascular and respiratory response to exercise: model-building and comparison with reported models-Reference-Cited by-同舟云学术

An integrated mathematical model of the cardiovascular and respiratory response to exercise: model-building and comparison with reported models

Published:2021-04-01 Issue:4 Volume:320 Page:H1235-H1260
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Sarmiento Carlos Andrés¹^ORCID,Hernández Alher Mauricio¹^ORCID,Serna Leidy Yanet²³^ORCID,Mañanas Miguel Ángel²³^ORCID

Affiliation:

1. Bioinstrumentation and Clinical Research Group, Bioengineering Program, Universidad de Antioquia UdeA, Medellin, Colombia

2. Department of Automatic Control and the Biomedical Engineering Research Centre of The Universitat Politècnica de Catalunya, Barcelona, Spain

3. Biomedical Research Networking Center in Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), Madrid, Spain

Abstract

This paper presents a new cardiorespiratory model focused on the prediction of the healthy human response under rest and aerobic dynamic exercise conditions. Simulation results of cardiorespiratory variables are compared against experimental data and two of the most current and complete cardiorespiratory models.

Funder

COLCIENCIAS - Sistema General de Regalías fondos CTeI del Departamento de Antioquia

MEC | Consejo Superior de Investigaciones Científicas

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00074.2020

Reference49 articles.

1. An integrated mathematical model of the human cardiopulmonary system: model validation under hypercapnia and hypoxia

2. Ventilatory control in hypercapnia and exercise: optimization hypothesis