Ventricular-arterial coupling and cardiovascular risk among young adults: The African-PREDICT study-Reference-Cited by-同舟云学术

Ventricular-arterial coupling and cardiovascular risk among young adults: The African-PREDICT study

Published:2023-08-01 Issue:2 Volume:325 Page:H362-H371
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Holm Hannes¹²^ORCID,Kruger Ruan³⁴^ORCID,Jujic Amra¹²^ORCID,Lamiral Zohra⁵⁶^ORCID,Uys Aletta Sophia³⁴^ORCID,Girerd Nicolas⁵⁶^ORCID,Magnusson Martin¹²³⁷^ORCID

Affiliation:

1. Department of Cardiology, Skåne University Hospital, Malmö, Sweden

2. Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden

3. Hypertension in Africa Research Team, North-West University, Potchefstroom, South Africa

4. MRC Research Unit for Hypertension and Cardiovascular Disease, North-West University, Potchefstroom, South Africa

5. INSERM, Centre d’Investigations Cliniques-1433, Université de Lorraine, Nancy, France

6. INSERM, CHRU Nancy, F-CRIN INI-CRCT, Nancy, France

7. Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden

Abstract

Assessing VAC is especially useful in heart failure and valvular heart disease, but less is known about VAC in the pathophysiology of CV disease risk in younger individuals. In young individuals without overt CV disease, we showed descriptive data regarding VAC, determined by PWV/GLS ratio, and explored the associations of VAC with clinical CV disease risk factors. Worse VAC, reflected by higher values of PWV/GLS, associated with high blood pressure and smoking in young adults.

Funder

National Research Foundation

South African Medical Research Council

United Kingdom Medical Research Council

Pfizer

Boehringer-Ingelheim

Novartis

Medi Clinic Hospital Group

Roche Diagnostics

Publisher

American Physiological Society

Subject