Cardiac stasis imaging, stroke, and silent brain infarcts in patients with nonischemic dilated cardiomyopathy

Author:

Rodríguez-González Elena1234,Martínez-Legazpi Pablo45ORCID,González-Mansilla Ana1234,Espinosa M. Ángeles1234,Mombiela Teresa1234,Guzmán De-Villoria Juan A.367,Borja Maria Guadalupe8,Díaz-Otero Fernando39,Gómez de Antonio Rubén310,Fernández-García Pilar37ORCID,Fernández-Ávila Ana I.1234,Pascual-Izquierdo Cristina310,del Álamo Juan C.11,Bermejo Javier1234

Affiliation:

1. Department of Cardiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain

2. Department of Medicine, Facultad de Medicina, Universidad Complutense, Madrid, Spain

3. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain

4. Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain

5. Department of Mathematical Physics and Fluids, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, Madrid, Spain

6. Department of Radiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain

7. Centro de Investigación Biomédica en Red de Salud Mental, Madrid, Spain

8. Department of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, California, United States

9. Department of Neurology, Hospital General Universitario Gregorio Marañón, Madrid, Spain

10. Department of Hematology, Hospital General Universitario Gregorio Marañón, Madrid, Spain

11. Division of Cardiology, Department of Mechanical Engineering, Center for Cardiovascular Biology, University of Washington, Seattle, Washington, United States

Abstract

Patients with nonischemic dilated cardiomyopathy (NIDCM) are at higher risk of stroke than their age-matched population. However, the risk of bleeding neutralizes the benefit of preventive oral anticoagulation. In this work, we show that in patients in sinus rhythm, the burden of stroke is related to intraventricular stasis metrics derived from echocardiography. Therefore, stasis metrics may be useful to personalize primary prevention anticoagulation in these patients.

Funder

Foundation for the National Institutes of Health

MEC | Instituto de Salud Carlos III

Sociedad Española de Cardiología

Publisher

American Physiological Society

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3