Hemodynamic simulation of complete transposition of the great arteries for optimal treatment strategies based on its circulatory physiology-Reference-Cited by-同舟云学术

Hemodynamic simulation of complete transposition of the great arteries for optimal treatment strategies based on its circulatory physiology

Published:2024-03-01 Issue:3 Volume:326 Page:H812-H820
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Sato Kaname¹^ORCID,Takamizawa Koichi¹,Ogawa Yosuke¹^ORCID,Tanaka Yu¹,Shiraga Kazuhiro¹,Masuda Hitomi¹,Matsui Hikoro¹^ORCID,Inuzuka Ryo¹,Senzaki Hideaki²³^ORCID

Affiliation:

1. Department of Pediatrics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

2. Comprehensive Support Center for Children’s Happy Life and Future, Nihon Institute of Medical Science University, Saitama, Japan

3. GK Choko: Comprehensive Support Center for Children’s Happy lives and Futures, Saitama, Japan

Abstract

Complete transposition of the great arteries (TGA) represents complex and unique circulation that is dependent on blood mixing through multiple interacting shunts. Consequently, the role of each shunt and the treatment strategy remain unclear. We developed a mathematical model of TGA circulation, revealing the significant influence of atrial septal defect (ASD) on oxygenation and hemodynamics. The blood flow pattern through the ASD reflects its hemodynamic impact and helps determine treatment strategies.

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00668.2023

Reference22 articles.

1. Role of prostaglandin E1 infusion in the management of transposition of the great arteries

2. Creation of an Atrial Septal Defect Without Thoracotomy

3. Hemodynamics in transposition of the great arteries with comparison to ventricular septal defect

4. The arterial Windkessel

5. Influence of Cardiac Function and Loading Conditions on the Myocardial Performance Index　– Theoretical Analysis Based on a Mathematical Model –