Vascular dysfunction and oxidative stress caused by acute formaldehyde exposure in female adults

Author:

Augenreich Marc1,Stickford Jonathon1,Stute Nina1,Koontz Laurel1,Cope Janet2,Bennett Cynthia3,Ratchford Stephen M.1

Affiliation:

1. Department of Health & Exercise Science, Appalachian State University, Boone, North Carolina

2. Department of Physical Therapy Education, Elon University School of Health Sciences, Elon, North Carolina

3. Department of Physician Assistant Studies, Elon University School of Health Sciences, Elon, North Carolina

Abstract

This study was the first to investigate the implications of acute formaldehyde (FA) exposure on adult female vascular function in the arms and legs. The main findings from this study were a decrease in conduit vessel function without any alteration to microvascular function following a 90-min FA exposure. Additionally, the oxidative stress marker malondialdehyde increased after FA exposure. Taken together, these results suggest acute FA exposure have deleterious implications for the vasculature and redox balance.

Funder

Elon University

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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