Impact of intraventricular septal fiber orientation on cardiac electromechanical function

Abstract

i) A dual-layer organization of fiber orientation in the intraventricular was identified in ex-vivo hearts of large mammalsii) The RV septum has a downwardly directed superficial layer, which is continuous with the moderator band.iii) Electrically, it produced a diamond activation pattern.iv) Electromechanically, little change in pressure volume loops were noticed but stress distribution was altered.v)Fiber distribution derived from diffusion tensor imaging should be considered for an accurate strain and stress analysis.