Isoproterenol improves hemodynamics and right ventricle-pulmonary artery coupling after heart transplantation-Reference-Cited by-同舟云学术

Isoproterenol improves hemodynamics and right ventricle-pulmonary artery coupling after heart transplantation

Published:2024-07-01 Issue:1 Volume:327 Page:H131-H137
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Levy David¹²^ORCID,Saura Ouriel¹²,Lucenteforte Manuela¹³,Collado Lledó Elena⁴,Demondion Pierre¹⁵,Hammoudi Nadjib⁶,Assouline Benjamin²⁷,Petit Matthieu¹²,Gautier Melchior¹²,Le Fevre Lucie¹²,Pineton de Chambrun Marc¹²⁸,Coutance Guillaume¹⁵,Berg Elodie¹⁵,Chommeloux Juliette¹²,Schmidt Matthieu¹²,Luyt Charles-Edouard¹²,Lebreton Guillaume¹⁵,Leprince Pascal¹⁵,Hékimian Guillaume¹²,Combes Alain¹²

Affiliation:

1. Institute of Cardiometabolism and Nutrition, Sorbonne Université, INSERM, UMRS_1166-ICAN, Paris, France

2. Service de Médecine Intensive-Réanimation, Institut de Cardiologie, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France

3. Department of Health Sciences, University of Milan, Milano, Italy

4. Acute Cardiovascular Care Unit, Department of Cardiology, Hospital Germans Trias i Pujol, Barcelona, Spain

5. Service de Chirurgie Cardiaque et Thoracique, Institut de Cardiologie, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France

6. Sorbonne Université, ACTION Study Group, INSERM UMR_S 1166 and Hôpital Pitié-Salpêtrière (Assistance Publique-Hôpitaux de Paris), Boulevard de l'hôpital, Paris, France

7. Intensive Care Medicine Unit, Division of Intensive Care, Department of Acute Medicine, University Hospital of Geneva, Geneva, Switzerland

8. Service de Médecine Interne 2, Centre de Référence Lupus Systémique, SAPL et Autres Maladies Auto-immunes et Systémiques Rares, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France

Abstract

This study offers a detailed and comprehensive hemodynamic investigation at the bedside, illustrating the favorable impact of isoproterenol on right ventricular-pulmonary arterial coupling and global hemodynamics. It elucidates the physiological effects of an underused inotropic strategy in a critical clinical scenario. By enhancing cardiac hemodynamics, isoproterenol has the potential to expedite right ventricular recovery and mitigate primary graft dysfunction, thereby reducing the duration of mechanical support and intensive care unit stay posttransplantation.

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00200.2024

Reference37 articles.

1. The Registry of the International Society for Heart and Lung Transplantation: Twenty-eighth Adult Heart Transplant Report—2011

2. Report from a consensus conference on primary graft dysfunction after cardiac transplantation

3. The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients

4. Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology

5. Cardiogenic Shock