Insulin stimulation reduces aortic wave reflection in adults with metabolic syndrome-Reference-Cited by-同舟云学术

Insulin stimulation reduces aortic wave reflection in adults with metabolic syndrome

Published:2021-06-01 Issue:6 Volume:320 Page:H2305-H2312
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Dotson Brielle L.¹,Heiston Emily M.¹²,Miller Stephanie L.¹,Malin Steven K.¹³⁴⁵⁶^ORCID

Affiliation:

1. Department of Kinesiology, University of Virginia, Charlottesville, Virginia

2. Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia

3. Department of Kinesiology and Health, Rutgers University, New Brunswick, New Jersey

4. Division of Endocrinology, Metabolism and Nutrition; Rutgers University, New Brunswick, New Jersey

5. New Jersey Institute for Food, Nutrition and Health, Rutgers University, New Brunswick, New Jersey

6. Institute of Translational Medicine and Science, Rutgers University, New Brunswick, New Jersey

Abstract

This study is one of the first to investigate the effects of insulin on central and peripheral hemodynamics in adults with metabolic syndrome. We provide evidence that insulin infusion reduces aortic wave reflection, potentially through a reduction in inflammation and/or via a potassium-mediated vascular response.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00975.2020

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