Postsurgery echocardiography can predict the amount of ischemia-reperfusion injury and the resultant scar size-Reference-Cited by-同舟云学术

Postsurgery echocardiography can predict the amount of ischemia-reperfusion injury and the resultant scar size

Published:2021-02-01 Issue:2 Volume:320 Page:H690-H698
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Yang Yijun¹²,Schena Giana J.¹²,Wang Tao¹²,Houser Steven R.¹²

Affiliation:

1. Independence Blue Cross Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania

2. Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania

Abstract

We believe our work is noteworthy due to its creation of standards for early evaluation of the level of myocardial injury in mouse models of ischemia-reperfusion. This improvement to study design could reduce the sample sizes used in evaluating therapeutics and lead to increased confidence in conclusions drawn regarding the therapeutic efficacy of treatments tested in these translational mouse models.

Funder

American Heart Association

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00672.2020

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