Potential effects of the hydrostatic pressure gradient on hyperemic and nonhyperemic pressure ratios-Reference-Cited by-同舟云学术

Potential effects of the hydrostatic pressure gradient on hyperemic and nonhyperemic pressure ratios

Published:2023-09-01 Issue:3 Volume:325 Page:H562-H568
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Florie Naomi H. M.¹,Eerdekens Rob¹^ORCID,Manzi Maria V.²^ORCID,Heinrichs Eduard³^ORCID,van ‘t Veer Marcel¹,van Royen Niels⁴,Tonino Pim A. L.¹,van Nunen Lokien X.⁴^ORCID

Affiliation:

1. Heart Center, Catharina Hospital, Eindhoven, The Netherlands

2. Uppsala University Hospital, Uppsala, Sweden

3. Cavis Technologies AB, Uppsala, Sweden

4. Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands

Abstract

This study systematically simulated the effect of hydrostatic pressure gradients (HPG) on real-world hyperemic and nonhyperemic pressure ratios, showing correction for HPG leads to reclassification in functional significance from 13.4 to 22.3% for different functional indices. This was most pronounced in nonhyperemic pressure ratios. A new pressure guidewire (Wirecath) is unaffected by HPG. The ongoing PW-COMPARE study (NCT04802681) prospectively analyzes the magnitude and importance of HPG by simultaneous FFR measurements.

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00305.2023

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