Relationships between circulating irisin levels, cardiorespiratory fitness, and cardiometabolic risk: a cross-sectional study in Japanese adults

Author:

Inoue Kenichiro12,Fujie Shumpei1,Kurose Satoshi3ORCID,Miyauchi Takumi3,Sanada Kiyoshi1ORCID,Kimura Yutaka3,Iemitsu Motoyuki1ORCID

Affiliation:

1. Faculty of Sport and Health Science, Ritsumeikan University, Shiga, Japan

2. Japan Society for the Promotion of Science, Tokyo, Japan

3. Health Science Center, Kansai Medical University, Osaka, Japan

Abstract

Circulating irisin levels gradually increased, and cardiometabolic risks gradually decreased with increasing cardiorespiratory fitness levels. The fitness levels required to increase irisin levels were moderate for young adults and lower than moderate for middle-aged and older adults. Moreover, circulating irisin levels are correlated with a reduction in cardiometabolic risk and an increase in cardiorespiratory fitness. These data suggest that circulating irisin levels are involved in the association between cardiorespiratory fitness and cardiometabolic risk.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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