Affiliation:
1. Department of Physiology and Biophysics, Rush University Medical Center, Chicago, Illinois
Abstract
This study provides conclusive evidence that mitochondrial Ca uptake and retention protects from Ca alternans, whereas uptake inhibition enhances Ca alternans. The data suggest pharmacological mitochondrial Ca cycling modulation as a potential therapeutic strategy for alternans-related cardiac arrhythmia prevention.
Funder
HHS | NIH | National Heart, Lung, and Blood Institute
Publisher
American Physiological Society
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology
Cited by
23 articles.
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