Regional beat-to-beat variability of repolarization increases during ischemia and predicts imminent arrhythmias in a pig model of myocardial infarction-Reference-Cited by-同舟云学术

Regional beat-to-beat variability of repolarization increases during ischemia and predicts imminent arrhythmias in a pig model of myocardial infarction

Published:2023-07-01 Issue:1 Volume:325 Page:H54-H65
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Amoni Matthew¹²,Ingelaere Sebastian¹²^ORCID,Moeyersons Jonathan³,Wets Dries¹,Tanushi Aldo¹,Van Huffel Sabine³,Varon Carolina³⁴^ORCID,Sipido Karin¹,Claus Piet⁵^ORCID,Willems Rik¹²^ORCID

Affiliation:

1. Experimental Cardiology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

2. Department of Cardiology, University Hospitals, Leuven, Belgium

3. Department of Electrical Engineering, STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium

4. Microgravity Research Center, Université Libre de Bruxelles, Brussels, Belgium

5. Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

Abstract

The key finding of this study is that BVR increases during AMI and surges before ventricular arrhythmia onset. This suggests that monitoring BVR may be useful for monitoring the risk of VF during and after AMI in the coronary care unit settings. Beyond this, monitoring BVR may have value in cardiac implantable devices or wearables.

Funder

European Space Agency

Fonds Wetenschappelijk Onderzoek

Onderzoeksraad, KU Leuven

Vlaamse regering

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00732.2022

Reference51 articles.