Cytosolic DNA sensor cGAS plays an essential pathogenetic role in pressure overload-induced heart failure
Author:
Affiliation:
1. Department of Cardiology, Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Center for Cardiovascular Translational Research, Peking University People’s Hospital, Beijing, China
Abstract
Funder
National Natural Science Foundation of China
Capital Health Research and Development of Special
Publisher
American Physiological Society
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology
Link
https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00097.2020
Reference43 articles.
1. Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association
2. STING-dependent sensing of self-DNA drives silica-induced lung inflammation
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4. Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure
5. STING and the innate immune response to nucleic acids in the cytosol
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