In vivo application and validation of a novel noninvasive method to estimate the end-systolic elastance

Abstract

In this study, we present a novel model-based method to estimate the left ventricular (LV) end-systolic elastance ( Ees) according to measurement of the patient’s arm-cuff pressure and a routine echocardiography examination. The proposed method was validated in vivo against invasive multiple-loop measurements of Ees, achieving high correlation and low bias. This tool could be most valuable for clinicians to assess the cardiovascular health of critically ill patients.