Effects of an hERG Activator, ICA-105574, on Electrophysiological Properties of Canine Hearts-Reference-Cited by-同舟云学术

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Effects of an hERG Activator, ICA-105574, on Electrophysiological Properties of Canine Hearts

Published:2013 Issue:1 Volume:121 Page:1-8
ISSN:1347-8613
Container-title:Journal of Pharmacological Sciences
language:en
Short-container-title:J Pharmacol Sci

Author:

Asayama Mahoko,Kurokawa Junko,Shirakawa Kiyoshi,Okuyama Hisashi,Kagawa Toshiki,Okada Jun-ichi,Sugiura Seiryo,Hisada Toshiaki,Furukawa Tetsushi

Publisher

Japanese Pharmacological Society

Subject

Pharmacology,Molecular Medicine

Reference30 articles.

1. 1 Sanguinetti MC, Jiang C, Curran ME, Keating MT. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the I_Kr potassium channel. Cell. 1995;81:299–307.

2. 2 Clancy CE, Rudy Y. Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death. Cardiovasc Res. 2001;50:301–313.

3. 3 Clancy CE, Kurokawa J, Tateyama M, Wehrens XH, Kass RS. K⁺ channel structure-activity relationships and mechanisms of drug-induced QT prolongation. Annu Rev Pharmacol Toxicol. 2003;43:441–461.

4. 4 Brugada R, Hong K, Dumaine R, Cordeiro J, Gaita F, Borggrefe M, et al. Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation. 2004;109:30–35.

5. 5 Gerlach AC, Stoehr SJ, Castle NA. Pharmacological removal of human ether-a-go-go-related gene potassium channel inactivation by 3-nitro-N-(4-phenoxyphenyl) benzamide (ICA-105574). Mol Pharmacol. 2010;77:58–68.

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