Downregulation of CYP3A and P-Glycoprotein in the Secondary Inflammatory Response of Mice With Dextran Sulfate Sodium–Induced Colitis and Its Contribution to Cyclosporine A Blood Concentrations-Reference-Cited by-同舟云学术

Downregulation of CYP3A and P-Glycoprotein in the Secondary Inflammatory Response of Mice With Dextran Sulfate Sodium–Induced Colitis and Its Contribution to Cyclosporine A Blood Concentrations

Published:2014 Issue:2 Volume:124 Page:180-191
ISSN:1347-8613
Container-title:Journal of Pharmacological Sciences
language:en
Short-container-title:J Pharmacol Sci

Author:

Kawauchi Shoji,Nakamura Tsutomu,Miki Ikuya,Inoue Jun,Hamaguchi Tsuneo,Tanahashi Toshihito,Mizuno Shigeto

Publisher

Japanese Pharmacological Society

Subject

Pharmacology,Molecular Medicine

Link

https://www.jstage.jst.go.jp/article/jphs/124/2/124_13141FP/_pdf

Reference46 articles.

1. 1 Zhou S, Chan SY, Goh BC, Chan E, Duan W, Huang M, et al. Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs. Clin Pharmacokinet. 2005;44:279–304.

2. 2 Paine MF, Hart HL, Ludington SS, Haining RL, Rettie AE, Zeldin DC. The human intestinal cytochrome P450 “pie”. Drug Metab Dispos. 2006;34:880–886.

3. 3 Jin M, Shimada T, Yokogawa K, Nomura M, Ishizaki J, Piao Y, et al. Site-dependent contributions of P-glycoprotein and CYP3A to cyclosporin A absorption, and effect of dexamethasone in small intestine of mice. Biochem Pharmacol. 2006;72:1042–1050.

4. 4 Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, et al. Membrane transporters in drug development. Nat Rev Drug Discov. 2010;9:215–236.

5. 5 Smit JW, Schinkel AH, Weert B, Meijer DK. Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted. Br J Pharmacol. 1998;124:416–424.

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