Hemostatic Action of OC-108, a Novel Agent for Hemorrhoids, Is Associated With Regional Blood Flow Arrest Induced by Acute Inflammation

Author:

Ono Takashi,Nakagawa Haruto,Fukunari Atsushi,Hashimoto Toshio,Komatsu Hirotsugu

Publisher

Japanese Pharmacological Society

Subject

Pharmacology,Molecular Medicine

Reference12 articles.

1. 1 Shi Z, Zhou J, He X. On treatment of third degree internal hemorrhoids with “Xiaozhiling” injection. J Trad Chin Med. 1981;1:115–120.

2. 2 Shi Z. Xiaozhiling four-step injection in treating hemorrhoids of stages III and IV – a sclerotherapeutic approach of thrombosing branches of artery rectalis superior. Chin J Trad W Med. 1997;3:246–249.

3. 3 Takamura H, Takano M, Ohba H, Fukano M, Iwadare J, Koganezawa S, et al. [Investigation of efficacy, safety and pharmacokinetics with OC-108, a novel agent for sclerosing therapy of internal hemorrhoids – early phase II study.] Jpn Pharmacol Ther. 2004;32:355–365. (text in Japanese with English abstract)

4. 4 Takano M, Iwadare J, Ohba H, Takamura H, Masuda Y, Matsuo K, et al. Sclerosing therapy of internal hemorrhoids with a novel sclerosing agent. Comparison with ligation and excision. Int J Colorectal Dis. 2006;21:44–51.

5. 5 Takano M, Sakaue R, Fukushima Y, Kage M. [Experimental study on the effect of sclerosing agents for hemorrhoids.] J Jpn Soc Coloproctol. 1994;47:140–151. (text in Japanese with English abstract)

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