Uncertainties in the measurement of relative doses in radiotherapy

Author:

Buliński Krzysztof12,Kuszewski Tomasz12,Wnuk Katarzyna12,Braziewicz Janusz12,Ślosarek Krzysztof34

Affiliation:

1. Institute of Physics , Jan Kochanowski University , Kielce , Poland

2. Holycross Cancer Center , Kielce , Poland

3. Collegium Medicum , Jan Kochanowski University , Kielce , Poland

4. Maria Skłodowska – Curie, National Research Institute of Oncology , Gliwice Branch , Gliwice , Poland

Abstract

Abstract Both the measurement of the dose and the measurement of its distribution, like any other measurements, are subject to measurement uncertainties. These uncertainties affect all dose calculations and dose distributions in a patient’s body during treatment planning in radiotherapy. Measurement uncertainty is not a medical physicist’s error, but an inevitable element of their work. Planning the dose distribution in a patient’s body, we often try to reduce it in the volume of critical organs (OaR - Organ at Risk) or increase the minimum dose in the PTV region by a few percent. It is believed that the measurement uncertainty should be taken into account in these calculations at the stage of treatment planning. The paper presents the method of calculating the measurement uncertainty for different physical quantities in radiotherapy as percentage depth dose, profile function and output factor, due to the fact that these quantities have a particular impact on the calculated dose distributions in a patient’s body. The uncertainties that must be taken into account in planning treatment the planned dose per fraction and real in PTV, maybe different up to 4%.

Publisher

Walter de Gruyter GmbH

Reference11 articles.

1. 1. Fraass B, Doppke K, Hunt M, et al. American Association of Physicists in Medicine Radiation Therapy Committee Task Group 53:Quality assurance for clinical radiotherapy treatment planning. Med Phys. 1998;25(10):1773-1829. https://doi.org/10.1118/1.598373

2. 2. Szydłowski H. Niepewności w pomiarach. Międzynarodowe standardy w praktyce. Wydawnictwo Naukowe UAM, Poznań 2001.

3. 3. International vocabulary of metrology – Basic and general concepts and associated terms (VIM). JCGM 200:2012. Available: https://www.bipm.org/en/publications/guides/vim.html

4. 4. Almond PR, Biggs PJ, Coursey BM, et al. AAPM’s TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams. Med Phys. 1999;26(9):1847-1870. https://doi.org/10.1118/1.598691

5. 5. Absorbed Dose Determination in External Beam Radiotherapy: An International Code of Practice for Dosimetry based on Standards of Absorbed Dose to Water. IAEA TRS-398, 2000.

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