Cancer in Parkinson’s Disease, a Review of Literature

Abstract

Abstract Background/Aim: The present study aimed to assess the conclusions of literature articles on the matter of cancer in Parkinson’s disease. Patients and Methods: Studies and articles that contained information on epidemiology, pathophysiological, clinical as well as associations and correlations on the topic of Parkinson’s disease and cancer were incorporated in the research too. Results: The prevalent part of the investigations and studies on the matter of Parkinson’s disease patients’ risk of cancer revealed a decreased lifetime risk in comparisson with non-PD subjects. In the literature, the most prevalent types of cancer among Parkinson’s disease patients were melanoma and other subtypes skin cancer and also, breast cancer. Conclusion: Epigenetic factors, gene–environment interactions, and problematic events can have an impact in the occurance and progression of Parkinson’s disease. Further, the mentioned factors can also determine the developing of cancer. Therefore, a complex and interesting relation between the two diseases is further to be discovered.