Biochemical Modifications Associated with Bladder Cancer

Abstract

Abstract Bladder cancer is the most common neoplasm of the urinary system, and urothelial carcinoma is the most common histological type of bladder cancer (approximately 90%), and represents the invasion of the basement membrane or lamina propria by urothelial cells. Most people with bladder cancer have hematuria and the doctor should be consulted as soon as possible and a specialist scheduled to examine the bladder with a camera - cystoscopy. The present study is a retrospective study that includes 174 patients from the Urology Clinic of the „Sfantul Apostol Andrei” County Emergency Clinical Hospital in Constanta in the period 2016-2020. In the study, the 174 patients were divided into 2 groups. The first group is a study group and includes patients with an anatomopathologically confirmed diagnosis of urothelial carcinoma, while the second, control group, contains patients without a diagnosis of urothelial carcinoma. This study analyzes the metabolic disorders associated with bladder cancer. There is a highly statistically significant association between hematuria and urothelial carcinoma. The present study confirms a significant association between urinary tract infection and bladder cancer. The infection is associated due to the presence of blood in the urine, being an environment for the development of bacterial cultures. A significant association is observed between hemoglobin and urothelial carcinoma, with patients developing anemia due to episodes of hematuria caused by the presence of bladder tumors.