Ethipatogenetic Study of Urothelial Carcinomas in the Urology Clinic of the County Clinical Hospital of Constanta

Abstract

Abstract Bladder cancer is the most common malignancy involving the urinary system, urothelial carcinoma of the upper tract is a rare subgroup of urothelial cancers with poor prognosis, being the most common histological type of bladder cancer (approximately 90%), manifesting as invasion of the basal membrane (or deeper) by neoplastic cells of urothelial origin. This type of carcinoma is more common in men than women, with a male to female ratio of 2:1, with men being 3 to 4 times more likely to develop bladder cancer than women. The present study is a retrospective study including 174 patients in the Urology Clinic of Constanta County St. Apostle Andrew Emergency Hospital in the period 2016-2020. Patients were divided into 2 groups: Group A and Group B. Group A includes patients with anatomopathologically confirmed diagnosis of urothelial carcinoma, while in Group B are patients who do not present a diagnosis of urothelial carcinomas. In this study the influence of environmental factors on the occurrence of urothelial carcinomas was compared in order to draw conclusions on the occurrence and development of these types of neoplasms.