A Polarized Light Microscopy Study in a Case of Morphea-Reference-Cited by-同舟云学术

A Polarized Light Microscopy Study in a Case of Morphea

Published:2020-02-01 Issue:1 Volume:26 Page:1-4
ISSN:1841-4036
Container-title:ARS Medica Tomitana
language:en
Short-container-title:

Author:

Liliana Mocanu¹,Sorin Deacu²,Polimaru Roman³,Mariana Aschie⁴

Affiliation:

1. County Clinical Emergency Hospital of Constanta

2. Forensic Medicine Service , Constanta

3. Private medicine practice , Constanta

4. University “Ovidius” of Constanta , Faculty of Medicine

Abstract

Abstract We report a case of plaque type of scleroderma with specific clinical features and conventional histopathology, with sclerosis and hipocellularity of fibroblasts and preservation of elastic tissue. We describe polarized light microscopy findings, on conventional stained slides and on picro sirius red stained slides. We appreciate that picro sirius red stain allows a better characterization of collagen fibres composition in papillary and reticular dermis, that is severely disturbed in morphea, with an inverse distribution of collagen fibres type I and III comparative with normal dermis.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.sciendo.com/pdf/10.2478/arsm-2020-0001

Reference8 articles.

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