The Influence of Obesity on the Evolution of SARS-COV2 Infection

Author:

Denisa-Gabriela Andrei12,Simona Lupsa2,Viorica Zamfir12,Ionut Stanciu13,Lupu I1,Tony Hangan14,Sergiu Chirila1,Elena Dantes12

Affiliation:

1. Faculty of Medicine , ‘Ovidius’ University of Constanta- Doctoral School of Medicine , Constanta , Romania

2. Clinical Hospital of Pneumophtisiology , Constanta , Romania

3. Department of Pulmonology Constanta County Clinical Emergency Hospital ‘Sf. Apostol Andrei’

4. Department of Dermatology Constanta County Clinical Emergency Hospital ‘Sf. Apostol Andrei’

Abstract

Abstract Aim: The issue of body weight has left a deep mark on the COVID-19 pandemic, where this category of patients has been linked to significant increases in morbidity and mortality due to infection. Conversely, due to the restrictions imposed, the pandemic has worsened the situation of overweight people. Our study conducted over a period of one year and five months aims to assess the prevalence of obesity among patients with SARS-COV2 infection in Constanta County. Material and method: This retrospective study included a number of 177 patients hospitalized with the diagnosis of SARS-COV2 infection in the Clinical Hospital of Pneumoftiziology Constanta. Results: 2483 of patients confirmed with SARS-COV2 infection were identified in our Department, out of which 302 had a body mass index over 30 kg/m2. We included a random sample of 95 men and 82 women in a database. The average age was 55 years. The most common comorbidities were hypertension (48%), diabetes (13%), and cardiovascular disease (12%). The most common symptoms were fever (67%), cough (58%), dyspnea (37%), and asthenia (29%). The radiological appearance showed the predominance of the moderate form (49%) and the severe form (22%). Antibiotic treatment was based on third-generation cephalosporins (53%), and the evolution was for improvement with a survival rate of 86%. Only one death was reported in our study. Conclusion: The body mass index influences the evolution of infected cases. Old age, male gender and associated comorbidities are risk factors for a poorer prognosis and greater complications in patients with SARS-COV2.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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