Contaminants of Medicinal Herbs and Herbal Products

Author:

Kosalec Ivan1,Cvek Josipa2,Tomić Siniša2

Affiliation:

1. Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia1

2. Agency for Medicinal Products and Medical Devices, Zagreb, Croatia2

Abstract

Contaminants of Medicinal Herbs and Herbal ProductsMedicinal plants have a long history of use in therapy throughout the world and still make an important part of traditional medicine. Thus, medicinal plants and herbal products must be safe for the patient (consumer). This review addresses biological contaminants (microbes and other organisms) and chemical contaminants (mycotoxins, toxic elements such as heavy metals, and pesticide residues) as major common contaminants of medicinal herbs and herbal products. To prevent and screen for contamination and ensure safety and conformity to quality standards, medicinal herbs and herbal products should be included in appropriate regulatory framework.

Publisher

Walter de Gruyter GmbH

Subject

Public Health, Environmental and Occupational Health,Toxicology

Reference105 articles.

1. Association Européenne des Spécialités Pharmaceutiques Grand Public (AESGP). Economic and Legal Framework for Non-Prescription Medicines. 15th ed. Brussels: AESGP; 2009.

2. World Health Organization (WHO). National policy on traditional medicine and regulation of herbal medicines report of a WHO global survey. Geneva: WHO; 2005.

3. World Health Organization (WHO). WHO guidelines for assessing quality of herbal medicines with reference to contaminants and residue. Geneva: WHO; 2007.

4. World Health Organization (WHO). WHO guidelines on safety monitoring of herbal medicines in pharmacovigilance systems. Geneva: WHO; 2004.

5. Toxic heavy metals and undeclared drugs in Asian herbal medicines;E Ernst;Trends Pharmacol Sci,2002

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