Genotype comparison of Candida albicans isolates from different clinical samples-Reference-Cited by-同舟云学术

Genotype comparison of Candida albicans isolates from different clinical samples

Published:2019-07-01 Issue:3 Volume:27 Page:327-332
ISSN:2284-5623
Container-title:Revista Romana de Medicina de Laborator
language:en
Short-container-title:

Author:

Bostănaru Andra-Cristina¹,Roșca Irina²,Minea Bogdan³,Năstasă Valentin¹,Foia Liliana³,Marincu Iosif⁴,Mares Mihai¹,Mederle Ovidiu-Alexandru⁴

Affiliation:

1. Ion Ionescu de la Brad University , Iași , Romania

2. Petru Poni Institute of Macromolecular Chemistry , Iasi , Romania

3. Gr. T. Popa University of Medicine and Pharmacy , Iași , Romania

4. Victor Babes University of Medicine and Pharmacy , Timisoara , Romania

Abstract

Abstract Background: Fungal infections are a health issue paradoxically fuelled by the developments in medical care. Objectives: Our study is an investigation on the correlation between the infection site and the genotypes of Candida albicans strains isolated from Romanian patients. Methods: A total number of 301 isolates from different clinical sites were investigated in terms of genotype determination. Results: The isolates were clustered in three groups according to their genotype: 55.81% showed genotype A, 14.62% genotype B, and 29.57% genotype C. Conclusions: No significant correlation was found between the genotype and the infection site, but a significant correlation was found between genotype C and isolates from HIV patients proving that C. albicans pathogenicity probably relies on factors related to the host.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/rrlm-2019-0027

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