DNA Methylation Biomarkers in Cancer Diagnostics-Reference-Cited by-同舟云学术

DNA Methylation Biomarkers in Cancer Diagnostics

Published:2024-04-01 Issue:1 Volume:24 Page:1-6
ISSN:1338-4139
Container-title:Acta Medica Martiniana
language:en
Short-container-title:

Author:

Ivana Baranova¹²,Marek Samec³,Renata Pecova¹,Martin Pec³,Zuzana Dankova²

Affiliation:

1. Department of Pathological Physiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava , Martin , Slovakia

2. Biobank for Cancer and Rare Diseases, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava , Martin , Slovakia

3. Department of Medical Biology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava , Martin , Slovakia

Abstract

Abstract Cancer development and progression are characterized by intricate genetic and epigenetic alternations, with DNA methylation playing a crucial role in this transformative process. Recent advancements in DNA methylation mapping technologies have significantly contributed to the identification of novel cancer biomarkers. We provide a short overview of Conformité Européenne-marked in vitro diagnostic tests designed to detect DNA methylation changes in oncology practice.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/acm-2024-0001

Reference21 articles.

1. Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Review Nat Rev Genet 2002; 3 (6): 415–28.

2. Koch A, Joosten SC, Feng Z, de Ruijter TC, Draht MX, et al. Analysis of DNA methylation in cancer: location revisited. Nat Rev Clin Oncol 2018; 15 (7): 459–466.

3. Davalos V, Esteller M. Cancer epigenetics in clinical practice. CA Cancer J Clin 2023; 73 (4): 376–424.

4. Taryma-Lesniak O, Sokolowska KE, Wojdacz TK. Current status of development of methylation biomarkers for in vitro diagnostic IVD applications. Clin Epigenetics 2020; 12 (1): 100.

5. Ilse P, Biesterfeld S, Pomjanski N, Wrobel C, Schramm M. Analysis of SHOX2 methylation as an aid to cytology in lung cancer diagnosis. Cancer Genomics Proteomics 2014; 11 (5): 251–258.