The multidisciplinary team for gastroenteropancreatic neuroendocrine tumours: the radiologist’s challenge

Author:

Granata Vincenza1,Fusco Roberta1,Setola Sergio Venanzio1,Castelguidone Elisabetta de Lutio di1,Camera Luigi2,Tafuto Salvatore3,Avallone Antonio3,Belli Andrea4,Incollingo Paola5,Palaia Raffaele4,Izzo Francesco4,Petrillo Antonella1

Affiliation:

1. Division of Radiology, “Istituto Nazionale Tumori IRCCS Fondazione Pascale – IRCCS di Napoli” , Naples , Italy

2. Division of Radiology, “Università degli Studi di Napoli Federico II” , Naples , Italy

3. Division of Gastrointestinal Oncology, “Istituto Nazionale Tumori IRCCS Fondazione Pascale – IRCCS di Napoli” , Naples , Italy

4. Division of Hepatobiliary Surgical Oncology, “Istituto Nazionale Tumori IRCCS Fondazione Pascale – IRCCS di Napoli” , Naples , Italy

5. Operative Unit of Genaral surgery and Kidney Transplantation, Advanced Biomedical Science Department University Federico II of Naples , Naples , Italy

Abstract

Abstract Background Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) are a heterogeneous group of tumours. An effective diagnosis requires a multimodal approach that combines evaluation of clinical symptoms, hormonelevels, radiological and nuclear imaging, and histological confirmation. Imaging plays a critical role in NETs diagnosis, prognosis and management, so the radiologists are important members of the multidisciplinary team. During diagnostic work-up two critical issues are present: firstly the need to identify tumor presence and secondly to define the primary site and assess regional and distant metastases. Conclusions The most appropriate imaging technique depends on the type of neuroendocrine tumour and the availability of specialized imaging techniques and expertise. There is no general consensus on the most efficient imaging pathway, reflecting the challenge in reliably detection of these tumours.

Publisher

Walter de Gruyter GmbH

Subject

Radiology, Nuclear Medicine and imaging,Oncology

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