2018 Chinese guidelines for the diagnosis and treatment of rheumatoid arthritis

Author:

Tian Xinping1,Wang Qian1,Li Mengtao1,Zhao Yan1,Zhang Zhiyi2,Huang Cibo3,Liu Yi4,Xu Huji5,Chen Yaolong6,Wu Lijun7,Su Yin8,Xiao Weiguo9,Zhang Miaojia10,Zhao Dongbao11,Sun Linyun12,Zuo Xiaoxia13,Lei Junqiang14,Li Xiaofeng1,Zeng Xiaofeng1

Affiliation:

1. Department of Rheumatology, Peking Union Medical College Hospital (PUMCH) , Chinese Academy of Medical Sciences, National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID) , Key Laboratory of Rheumatology and Clinical Immunology , Ministry of Education, Chinese Rheumatism Data Center (CRDC) , Chinese SLE Treatment and Research Group (CSTAR) , Beijing , China

2. Department of Rheumatology , the First Affiliated Hospital Affiliated to Harbin Medical University , Harbin , Heilongjiang Province , China

3. Department of Rheumatology , Beijing Hospital , Beijing , China

4. Department of Rheumatology and Immunology , West China Hospital , Sichuan University , Chengdu , Sichuan Province , China

5. Department of Rheumatology and Immunology , Shanghai Changzheng Hospital , the Second Military Medical University , Shanghai , China

6. Institute of Health Data Science , Lanzhou University , Chinese GRADE Center , Lanzhou , Gansu Province , China

7. Department of Rheumatology , Xinjiang Uygur Autonomous Region People's Hospital , Urumuqi , Xinjiang Uygur Autonomous Region , China

8. Department of Rheumatology , Peking University People's Hospital , Beijing , China

9. Department of Rheumatology , The First Affiliated Hospital of China Medical University , Shenyang , Liaoning Province , China

10. Department of Rheumatology , The First Affiliated Hospital with Nanjing Medical University . Nanjing , JiangSu Province , China

11. Department of Rheumatology and Immunology , Changhai Hospital, The Second Military Medical University/Naval Medical University , Shanghai , China

12. Department of Rheumatology , Nanjing Drum Tower Hospital of Nanjing University Medical School

13. Department of Rheumatology and Immunology , Xiangya Hospital of Central South University , Rheumatic Diseases Research Center of Hunan Province , Changsha , China

14. Department of Radiology , The First Hospital of Lanzhou University , Lanzhou , Gansu Province , China

Abstract

Abstract A multidisciplinary guideline development group was established to formulate this evidence-based diagnosis and treatment guidelines for rheumatoid arthritis (RA) in China. The grading of recommendations, assessment, development, and evaluation (GRADE) system was used to rate the quality of the evidence and the strength of recommendations, which were derived from research articles and guided by the analysis of the benefits and harms as well as patients’ values and preferences. A total of 10 recommendations for the diagnosis and treatment of RA were developed. This new guideline covered the classification criteria, disease activity assessment and monitoring, and the role of disease modifying antirheumatic drugs (DMARDs), biologics, small molecule synthetic targeting drugs, and glucocorticoids in the treat-to-target approach of RA. This guideline is intended to serve as a tool for clinicians and patients to implement decision-making strategies and improve the practices of RA management in China.

Publisher

Walter de Gruyter GmbH

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