Dependence between Cu concentration in the liver, kidneys and skeletal muscles of canine females

Abstract

AbstractThe aim of the investigations was the determination of the Cu contents in the liver, kidneys and skeletal muscles of canine females. Material for research was collected post mortem from 45 animals aged 1 to 18 years coming from the Warsaw area. The effect of the health state, age and life conditions on the distribution of copper in the investigated organs was estimated. That element was determined using the method of inductively coupled plasma-atomic emission spectrometry (ICP-AES). In the liver, the average Cu contents amounted to 24.04 mg kg−1 wet weight, in kidneys to 2.90 mg kg−1 wet weight and in muscles to 0.94 mg kg−1 wet weight. The highest values of copper content in particular tissues and organs were noted in the group of animals with neoplastic changes. In respect to the animal age the highest mean values of the copper content were noted in the oldest animals. They amounted to 30.97 mg kg−1 in the liver, 3.34 mg kg−1 in kidneys and 1.18 mg kg−1 wet weight in muscles. Considering life conditions of the dogs it was observed that the higher mean values in all the investigated organs occurred in dogs coming from the urban areas.