Neutrophil to lymphocyte count ratio as a biomarker of bacterial infections-Reference-Cited by-同舟云学术

Neutrophil to lymphocyte count ratio as a biomarker of bacterial infections

Published:2012-04-01 Issue:2 Volume:7 Page:258-261
ISSN:2391-5463
Container-title:Open Medicine
language:
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Author:

Holub Michal¹,Beran Ondřej¹,Kaspříková Nikola²,Chalupa Pavel¹

Affiliation:

1. 1Department of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University in Prague and University Hospital Bulovka, CZ-180 81, Prague, Czech Republic

2. 2Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University in Prague, CZ-120 00, Prague, Czech Republic

Abstract

AbstractThe implementation of new markers of bacterial infection into clinical practice is hindered by their costs. We assessed the potential use of the neutrophil to lymphocyte count ratio (NLCR) to discriminate between bacterial and viral infections. NLCR was evaluated in 45 patients with bacterial infections: 24 patients with viral infections and 18 healthy adults. The medians of NLCR were 11.73 in bacterial infections, 2.86 in viral infections and 1.86 in controls. The NLCR cut-off value of 6.2 exhibited a sensitivity value of 0.91 and a specificity value of 0.96 for bacterial infection. These results suggest a diagnostic potential for NLCR.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

http://link.springer.com/content/pdf/10.2478/s11536-012-0002-3.pdf

Reference19 articles.

1. Adams NG. Diagnostic use of C-reactive protein in bacteraemic emergency department patients. Emerg Med Australan 2005; 17: 371–375

2. Ho KM, Lipman J. An update on C-reactive protein for intensivists. Anaesth Intensive Care 2009; 37: 234–241

3. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993; 34: 515–518

4. Russell JA. Management of sepsis. N Engl J Med 2006; 355: 1699–1713. Erratum in: N Engl J Med 2006; 355: 2267

5. Chalupa P, Beran O, Herwald H, Kaspříková N, Holub M. Evaluation of potential biomarkers for the discrimination of bacterial and viral infections. Infection 2011; 39: 411–417

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