Comparison of the Yield of Very Low Nicotine Content Cigarettes to the Top 100 United States Brand Styles-Reference-Cited by-同舟云学术

Comparison of the Yield of Very Low Nicotine Content Cigarettes to the Top 100 United States Brand Styles

Published:2019-08-01 Issue:6 Volume:28 Page:253-266
ISSN:1612-9237
Container-title:Beiträge zur Tabakforschung International/Contributions to Tobacco Research
language:en
Short-container-title:

Author:

Carmines Ed¹,Gillman I. Gene²

Affiliation:

1. Carmines Consulting, LLC, Scottsdale , AZ, USA

2. Enthalpy Analytical LLC, Durham , NC, USA

Abstract

Summary The objective of this work was to compare the nicotine content and yield of new very low nicotine content cigarettes (VLN™) to the top 100 cigarette brand styles in the United States. Nicotine in tobacco filler and nicotine in smoke were measured. On a dry weight basis, VLN™ cigarettes averaged 0.5 mg of nicotine/g tobacco as compared to 19.4 for the top 100 brand styles in the United States. On a cigarette basis, VLN™ cigarettes contained 0.27 mg of nicotine compared to 12 mg for the top brands. On an ISO smoke yield basis, VLN™ produced 0.03 mg nicotine/cig compared to 0.903 mg nicotine/cig for the leading brands. VLN™ cigarettes contained > 95% less nicotine on a per gram basis of tobacco or per cigarette basis than the top 100 brand styles in the U.S. VLN™ cigarettes yielded > 95% less nicotine in smoke than the top brand styles in the United States.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/cttr-2019-0005

Reference33 articles.

1. 1. Benowitz, N.L. and J.E. Henningfield: Establishing a Nicotine Threshold for Addiction. The Implications for Tobacco Regulation; N. Engl. J. Med. 331 (1994) 123–125. DOI: 10.1056/NEJM19940714331021210.1056/NEJM199407143310212

2. 2. Federal Drug Association (FDA), Commissioner of the FDA: Press Announcements - FDA Announces Comprehensive Regulatory Plan to Shift Trajectory of Tobacco-related Disease, Death; FDA News Release July 28,2017. Available at: https://www.fda.gov/news-events/press-announcements/fda-announces-comprehensive-regulatory-plan-shift-trajectory-tobacco-related-disease-death (accessed June 28, 2019).

3. 3. Layton, L: FDA Should Use its Power to Lower Nicotine in Cigarettes, Former Chief Says; Washington Post June 17, 2010. Available at http://www.washingtonpost.com/wp-dyn/content/article/2010/06/16/AR2010061605340.html?noredirect=on (accessed June 28, 2019).

4. 4. Federal Drug Association (FDA), Commissioner of the FDA: Speeches by FDA Officials - Protecting American Families: Comprehensive Approach to Nicotine and Tobacco; Speech June 28, 2017. Available at: https://www.fda.gov/news-events/speeches-fda-officials/protectingamerican-families-comprehensive-approach-nicotine-and-tobacco-06282017 (accessed June 28, 2019).

5. 5. Food and Drug Administration (FDA): Tobacco Product Standard for Nicotine Level of Combusted Cigarettes; 83 Fed. Reg. 11818 (2018). Available at: https://www.federalregister.gov/d/2018-05345 (accessed July 25, 2019).

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development of pulsed intravenous nicotine infusions as a model for inhaled nicotine in humans;Psychopharmacology;2022-05-13

2. Plasma Menthol Glucuronide as a Biomarker for the Behavioral Effects of Menthol and Nicotine in Humans;Frontiers in Pharmacology;2022-03-31

3. The relative impact of acute nicotine and tobacco administration on craving, withdrawal, and cigarette self-administration in dependent and nondependent smokers.;Experimental and Clinical Psychopharmacology;2021-12

4. Acute subjective sensory perceptions predict relative reinforcing effects of smoked nicotine;Addictive Behaviors;2021-06

5. Acute nicotine reinforcement requires ability to discriminate the stimulus effects of nicotine.;Experimental and Clinical Psychopharmacology;2020-10-29