Tobacco-specific N-Nitrosamines [TSNA] in Green Mature and Processed Tobacco Leaves from India-Reference-Cited by-同舟云学术

Tobacco-specific N-Nitrosamines [TSNA] in Green Mature and Processed Tobacco Leaves from India

Published:1987-12-01 Issue:1 Volume:14 Page:29-32
ISSN:1612-9237
Container-title:Beiträge zur Tabakforschung International/Contributions to Tobacco Research
language:en
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Author:

Bhide SV¹,Nair J¹,Maru GB¹,Nair UJ¹,Kameshwar Rao BV²,Chakraborty MK³,Brunnemann KD⁴

Affiliation:

1. Carcinogenesis Division, Cancer Research Institute, Tata Memorial Centre, Bombay (Parel), India

2. Department of Biochemistry, Central Tobacco Research Institute, Rajahmundry, India

3. Department of Biochemistry (Tobacco Project), Gujarat Agricultural University, Anand, India

4. Naylor Dana Institute for Disease Prevention, American Health Foundation, Valhalla, N. Y., U.S.A.

Abstract

Abstract Tobacco-specific N-nitrosamines [TSNA] and tobacco alkaloids were determined in green mature tobacco leaves, sun-dried leaves and processed tobacco from the species N. rustica and N. tabacum cultivated in two different locations. Analyses showed the presence of TSNA in green mature tobacco leaves and the levels of TSNA increased further upon sun-drying and processing. N. rustica showed relatively higher amounts of nornicotine as well as of N’-nitrosonornicotine [NNN]. A clear correlation between the amount of nicotine and nornicotine and the use of fertilizers was not found.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/cttr-2013-0581

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1. Use of autoclave extraction-supercritical fluid chromatography/tandem mass spectrometry to analyze 4-(methylintrosamino)-1-(3-pyridyl)-1-butanone and N’-nitrosonornicotine in tobacco;Journal of Chromatography A;2019-06

2. Tobacco-Specific Nitrosamines in the Tobacco and Mainstream Smoke of U.S. Commercial Cigarettes;Chemical Research in Toxicology;2016-12-21