Antiparasitic properties of homoallylamines and related compounds-Reference-Cited by-同舟云学术

Antiparasitic properties of homoallylamines and related compounds

Published:2006-01-01 Issue:1 Volume:51 Page:
ISSN:1896-1851
Container-title:Acta Parasitologica
language:
Short-container-title:

Author:

Gómez-Barrio Alicia,Montero-Pereira David,Nogal-Ruiz Juan,Escario José,Muelas-Serrano Susana,Kouznetsov Vladimir,Vargas Méndez Leonor,Urbina Gonzáles Juan,Ochoa Carmen

Abstract

AbstractA study of some antiparasitic properties of several homoallylamines and related tetrahydroquinolines and quinolines, previously described, was carried out using in vitro activity assays against the epimastigote form of Trypanosoma cruzi and against Trichomonas vaginalis. Unspecific cytotoxicity against murine macrophages was also studied. Although the antichagasic and trichomonacidal activities are not comparable to those of the standard drugs, nifurtimox and metronidazole, some of the compounds exhibit an interesting specific antiparasitic activity.

Publisher

Walter de Gruyter GmbH

Subject

Parasitology

Link

http://link.springer.com/content/pdf/10.2478/s11686-006-0010-z.pdf

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