How anti-c in a D– patient prompted lifesaving work between a transfusion service and a blood center reference laboratory

Author:

Patch Gavin1,Maurer Joan2,Sendilnathan Arun3,Leak Christine3,Nartowicz Elizabeth1,Kavitsky Victoria2,Facey Dexter2,Nance Sandra T.2,Keller Margaret A.2

Affiliation:

1. Solvita, Immunohematology Reference Laboratory and Hospital Laboratory Services , Dayton , OH United States

2. American Red Cross, Biomedical Services, American Rare Donor Program , Philadelphia , PA , Pennsylvania

3. Kettering Health Cancer Center at Hamilton , Department of Hematology Oncology , Hamilton , OH , Canada

Abstract

Abstract This case report showcases an extraordinary collaboration to support the transfusion needs of a patient with a rare phenotype and long-standing anemia due to gastrointestinal bleeding. This report describes the Immunohematology Reference Laboratory testing and logistics of rare blood provision over an 11-year period, as well as a summary of the hematologic, gastroenterologic, and surgical interventions. This case illustrates how a strong collaboration among the clinical team, laboratory, blood center, and the rare donor community facilitated successful management of this patient’s anemia until the patient could receive life-changing treatment.

Publisher

Walter de Gruyter GmbH

Reference6 articles.

1. Nance S, Arndt P, Garratty G. Predicting the clinical significance of red cell alloantibodies using a monocyte monolayer assay. Transfusion 1987;27:449–52.

2. Meny GM, Flickinger C, Marcucci CJ. The American Rare Donor Program. Crit Care 2013;28:110.e9–18. doi:10.1016/j.jcrc.2012.02.017.

3. Keller MA, Nance ST, Kavitsky V et al. The American Rare Donor Program: twenty-five years supporting rare blood needs. Immunohematology In press.

4. Maurer J, Nance S, Kavitsky V, Facey D, Keller M. High prevalence antigen negative unit requests: what if it includes being O negative? Transfusion 2021;35(Suppl 3):159–60A.

5. Maurer J, Nance S, Kavitsky V, Facey D, Keller M . When rare blood goes overseas. Transfusion 2021;35(Suppl 3):80A.

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