Reactionary Versus Reparative Dentine in Deep Caries-Reference-Cited by-同舟云学术

Reactionary Versus Reparative Dentine in Deep Caries

Published:2019-02-01 Issue:1 Volume:25 Page:15-21
ISSN:1841-4036
Container-title:ARS Medica Tomitana
language:en
Short-container-title:

Author:

Alexandru-Andrei Iliescu¹,Irina-Maria Gheorghiu²,Mihaela Tănase³,Andrei Iliescu⁴,Loredana Mitran⁵,Mitran M.⁶,Paula Perlea⁴

Affiliation:

1. Department of Oral Rehabilitation, Faculty of Dental Medicine , UMF Craiova

2. Department of Restorative Odontotherapy, Faculty of Dental Medicine , UMF “Carol Davila” Bucharest

3. Department of Oral Implantology, Faculty of Dental Medicine , UMF “Carol Davila” Bucharest

4. Department of Endodontics, Faculty of Dental Medicine , UMF “Carol Davila” Bucharest

5. Department of Otorhinolaryngology , Elias Hospital

6. Department of Obstetrics and Gynecology, Faculty of Medicine , UMF “Carol Davila” Bucharest

Abstract

Abstract The dentine-pulp complex response in deep caries is histological characterized by tertiary formation and mild chronic pulp inflammation. The quiescent primary odontoblasts are reactivated, laying down reactionary tertiary dentine. In more severe carious damage the primary odontoblasts die and reparative tertiary dentine is secreted by odontoblast-like cells, which are differentiated in adult teeth mainly from dental pulp stem cells DPSC. Though associated with reversible pulpitis DPSC still preserve in deep caries the capability of migration, proliferation and differentiation. Some common mechanisms of molecular signals involved in tertiary dentine formation might also explain the balance between inflammation and regeneration of dentine-pulp complex.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.sciendo.com/pdf/10.2478/arsm-2019-0004

Reference24 articles.

1. 1. Luukko K, Kettunen P, Fristad I, E B. Cohen’s pathways of the pulp.. In: KM H, S C, editors. Structure and functions of the dentin-pulp complex St.Louis Mosby Elsevier; 2011. p. 452-503.

2. 2. Smith, A.J. Dentin formation and repair. In: Hargreaves, K.M. & Goodis, H.E. (2002). Seltzer and Bender’s dental pulp. Quintessence, Carol Stream (pp.41-62).

3. 3. Olgart, L. & Bergenholtz, G. The dentine-pulp complex: responses to adverse influences. In: Bergenholtz, G., Hørsted-Bindslev, P. & Reit, C. Textbook of endodontology. (2003). 1st ed, Blackwell Munksgaard, Oxford (pp.21-42).

4. 4. Paula-Silva FW, Ghosh A, Silva LA, Kapila YL. TNF-alpha promotes an odontoblastic phenotype in dental pulp cells. J Dent Res. 2009;88(4):339-44.

5. 5. Choi BD, Jeong SJ, Wang G, Kim HJ, Kim BO, Hwang HK, et al. Temporal induction of secretory leukocyte protease inhibitor (SLPI) in odontoblasts by lipopolysaccharide and wound infection. J Endod. 2009;35(7):997-1002.

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Penetration of Silver Diamine Fluoride in Deep Carious Lesions of Human Permanent Teeth: An In Vitro Study;International Journal of Dentistry;2021-12-22

2. Validation of Roberts’ method using root canal width patterns as a mandibular maturity marker in determining the 18-year threshold;International Journal of Legal Medicine;2021-02-15