Antivirals for Virus Induced Exacerbations of Asthma and COPD Treatment

Author:

Cristina Grigorescu1,Antonela Antoniu Sabina1,Ruxandra Oţelea Marina2,Antohe Ileana1,Petronela Fildan Ariadna3,Anton Arghir Ioan3,Doina Tofolean Ecaterina3

Affiliation:

1. University of Medicine and Pharmacy “Gr. T. Popa”, Iasi , Romania

2. University of Medicine and Pharmacy “Carol Davila” , Bucharest , Romania

3. Faculty of Medicine , University “Ovidius” of Constanta , Romania

Abstract

Abstract Viral respiratory infections in patients with asthma or chronic obstructive pulmonary disease (COPD) can cause severe exacerbations, increasing the risk of secondary bacterial infections and having a significant impact on disease-related morbidity and mortality. Several antivirals such as oseltamivir and zanamivir evaluated in influenza and other virus-induced respiratory infections are discussed in this review as a starting point of their potential use in improving the outcome of asthma and COPD exacerbations. However, the efficacy of antiviral therapy for asthma/COPD exacerbations needs a further evaluation.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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