Importance of Prandial Glucose Regulation in the Management of Cardiovascular Complications in Type 2 Diabetes Mellitus

Abstract

AbstractThere is a worldwide epidemic increase in the number of type 2 diabetes (T2DM)patients who frequently associate with cardiovascular disease (CVD). There are datasuggesting that glycemic control does not substantially reduce CVD risk buthyperglycemia increases the risk of CVD. This apparent paradox could be explainedby the role of post-prandial hyperglycemia in the pathogenesis of cardiovascularcomplications in T2DM. There is numerous evidences, both experimental andclinical, for this association but controversies on this topic persist. The aim of thispaper was to review the current literature regarding the role of postprandial glucosein the genesis of CVD in T2DM.